Gommans J M, van den Hurk J J, Bergers M, van Erp P, Mier P D, Roelfzema H
Br J Dermatol. 1982 Mar;106(3):317-22. doi: 10.1111/j.1365-2133.1982.tb01730.x.
The glycocalyx of epidermal keratinocytes from psoriatic patients has been investigated by means of lectins. Striking changes were found in the levels of glucose and/or mannose (concanavalin A) and of N-acetylglucosamine and/or sialic acid (wheat germ agglutinin) on the surface of cells from the psoriatic lesion. Smaller but significant changes were seen in the clinically uninvolved epidermis of the patient. A marked increase in the affinity of the cell surface for Ulex europus agglutinin (fucose-specific) confirms our previous reports of structural alterations in fucose-containing oligosaccharides in psoriasis.
通过凝集素对银屑病患者表皮角质形成细胞的糖萼进行了研究。在银屑病皮损处细胞表面的葡萄糖和/或甘露糖（伴刀豆球蛋白A）以及N-乙酰葡糖胺和/或唾液酸（麦胚凝集素）水平上发现了显著变化。在患者临床上未受累的表皮中也观察到较小但显著的变化。细胞表面对欧洲荆豆凝集素（岩藻糖特异性）亲和力的显著增加证实了我们之前关于银屑病中含岩藻糖寡糖结构改变的报道。
