Lavallée M, Michel R P, Popkin D R
Can J Surg. 1982 Mar;25(2):191-3.
The authors report a case of immunoblastic lymphosarcoma of B cells with an unusual presentation. Laparotomy on a 67-year-old women with an abdominal mass revealed extensive peritoneal seeding resembling carcinomatosis. At autopsy, immunoblastic lymphosarcoma, probably originating in the bowel wall, was found. It was studied by light, immunofluorescent and electron microscopy. Histologic examination showed monomorphic proliferation of malignant immunoblasts with plasmacytoid features. Immunofluorescent microscopy was positive for intracytoplasmic IgG, IgA, kappa and lambda light chains. The presence of diffuse peritoneal seeding in patients with malignant lymphomas is not well documented. The clinical and pathologic features of this entity and its relation to Mediterranean lymphoma are discussed.
作者报告了一例具有不寻常表现的B细胞免疫母细胞性淋巴瘤病例。一名67岁有腹部肿块的女性接受剖腹手术，发现广泛的腹膜种植，类似癌转移。尸检时发现免疫母细胞性淋巴瘤，可能起源于肠壁。对其进行了光镜、免疫荧光和电镜研究。组织学检查显示具有浆细胞样特征的恶性免疫母细胞呈单形性增殖。免疫荧光显微镜检查显示胞浆内IgG、IgA、κ和λ轻链呈阳性。恶性淋巴瘤患者出现弥漫性腹膜种植的情况鲜有文献记载。本文讨论了该实体的临床和病理特征及其与地中海淋巴瘤的关系。
