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[1979 - 1980年分离的甲型(H3N2)流感病毒血凝素抗原组成特征]

[Characteristics of the antigenic composition of influenza A (H3N2) virus hemagglutinins isolated 1979-1080].

作者信息

Isaeva E I, Rovnova Z I

出版信息

Vopr Virusol. 1982 Jan-Feb(1):16-20.

PMID:6176071
Abstract

The results of comparative immunological analysis of epidemic influenza virus strains of 1979-1980 indicate an emergence in the antigenic composition of virus hemagglutinins of two qualitatively new antigenic determinants differing from those of previously investigated influenza H0N1, H1N1, H2N2, H3N2 viruses. It is suggested that the viruses of recent years having completely lost the relationship with the ancestor of the H3N2 subtype and having very little similarity with viruses occuring in 1975-1978 are precursors of the emergence of a new antigenic variant.

摘要

1979 - 1980年流行性感冒病毒株的比较免疫学分析结果表明,病毒血凝素的抗原组成中出现了两种性质上全新的抗原决定簇,它们不同于先前研究的H0N1、H1N1、H2N2、H3N2型流感病毒的抗原决定簇。有人认为,近年来的病毒已完全与H3N2亚型的祖先失去关联,且与1975 - 1978年出现的病毒相似度极低,它们是一种新抗原变体出现的前兆。

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