Isaeva E I, Rovnova I Z, Platonova A L, Kosiakov P N
Vopr Virusol. 1986 Mar-Apr;31(2):153-7.
The study of the antigenic composition of hemagglutinins of influenza H3N2 viruses isolated during epidemic outbreaks in 1979-1983, carried out by means of monospecific antibodies to individual antigenic determinants, showed heterogeneity of the antigenic structure of epidemically active variants. Some variants were antigenically identical to A/Bangkok/1/79 virus. Hemagglutinin structure of A/Shanghai/31/80, A/Philippines/2/82 and the like was found to contain a qualitatively new antigenic determinant heretofore undetectable in H1N1, H3N2 viruses.
通过针对各个抗原决定簇的单特异性抗体,对1979年至1983年流行暴发期间分离出的H3N2流感病毒血凝素的抗原组成进行研究,结果显示流行活跃变体的抗原结构具有异质性。一些变体在抗原性上与A/曼谷/1/79病毒相同。发现A/上海/31/80、A/菲律宾/2/82等病毒的血凝素结构含有一种此前在H1N1、H3N2病毒中未检测到的全新抗原决定簇。