Ismaĭlova I M, Isaeva E I
Vopr Virusol. 1984 Jan-Feb;29(1):69-74.
A comparative immunological analysis of the antigenic structure of hemagglutinins of influenza H2N2 viruses isolated in 1957-1967 was carried out by the method of specific adsorption of highly active antiviral rabbit sera. The hemagglutinins of the viruses under study were shown to contain at least three antigenic determinants changing in the course of evolution, one of them shared by all the viruses of the H2N2 subtype remaining antigenically stable since 1957 until 1967.
采用高活性抗病毒兔血清特异性吸附法,对1957年至1967年间分离的H2N2型流感病毒血凝素的抗原结构进行了比较免疫学分析。研究中的病毒血凝素显示至少含有三个在进化过程中发生变化的抗原决定簇,其中一个为H2N2亚型的所有病毒所共有,自1957年至1967年抗原性保持稳定。