正常人皮肤和基底细胞癌中的透明连接蛋白
Hyaluronectin in normal human skin and in basal cell carcinoma.
作者信息
Delpech A, Delpech B, Girard N, Boullie M C, Lauret P
出版信息
Br J Dermatol. 1982 May;106(5):561-8. doi: 10.1111/j.1365-2133.1982.tb04559.x.
Abstract
The localization of hyaluronectin has been studied in normal skin and in basal cell carcinoma. In fetal skin it is abundant in the dermis but absent from the epidermis, and in adult skin it is totally absent except in the hair sheaths and bulbs. In basal cell carcinoma it is abundant only in the stroma reaction. The presence of this protein in mesenchymatous tissues seems to be linked to zones of physiological or neoplastic proliferation.
摘要
已对正常皮肤和基底细胞癌中的透明连接蛋白定位进行了研究。在胎儿皮肤中，它在真皮中含量丰富，但表皮中不存在；在成人皮肤中，除了毛鞘和毛球外，它完全不存在。在基底细胞癌中，它仅在间质反应中含量丰富。这种蛋白质在间充质组织中的存在似乎与生理或肿瘤性增殖区域有关。
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