用人成纤维细胞单层培养物生产β-干扰素。病毒（新城疫病毒）和合成多核苷酸（聚肌苷酸-聚胞苷酸）诱导的比较研究。
Production of IFN beta with human fibroblasts in monolayer cultures. Comparative studies of induction with virus (NDV) and synthetic polynucleotides (poly I - poly C).
作者信息
Frappa J, Trotemann P, Beaudry Y, Fontanges R
出版信息
Dev Biol Stand. 1981;50:185-92.
PMID:6176485
Abstract
A comparative study of the production of IFN beta by human skin fibroblasts in monolayers was carried out using induction by NDV and poly I - poly C. The induction by polynucleotides produced significantly higher IFN beta titers. An attempt to grow those diploid cells on microcarriers resulted in a failure.
摘要
利用新城疫病毒（NDV）和聚肌胞苷酸（poly I - poly C）诱导，对单层培养的人皮肤成纤维细胞产生β干扰素的情况进行了比较研究。多核苷酸诱导产生的β干扰素效价显著更高。尝试在微载体上培养这些二倍体细胞，但未成功。
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