Butterworth T
Cutis. 1982 Apr;29(4):363-4, 367.
Accumulated evidence indicates that leukonychia striata and leukonychia totalis are distinct entities transmitted by automonal dominant gene. Much less secure is the status of leukonychia partialis in which the nail is white proximally and pink near its free edge. Leukonychia totalis and leukonychia partialis have occurred in different members of the same family and on different digits of an individual simultaneously, and either has presented as the clinical manifestation in an individual at different times. The two conditions are probably expressions of the same genetic defect. Historically, the term leukonychia totalis has priority over leukonychia partialis and the former form should be used, with the latter considered a variation of it.
越来越多的证据表明,线状白甲和全白甲是由常染色体显性基因传递的不同病症。而近端甲呈白色、游离缘附近呈粉红色的部分白甲的情况则不太明确。全白甲和部分白甲曾出现在同一家庭的不同成员身上,也同时出现在同一个体的不同手指上,并且任何一种都可能在不同时间成为个体的临床表现。这两种情况可能是同一基因缺陷的表现。从历史角度来看,全白甲这一术语比部分白甲出现得更早,应使用前者,而后者可视为前者的一种变体。