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人类听觉诱发电位的头皮分布。II. 听觉皮层源重叠及参与的证据。

Scalp distribution of human auditory evoked potentials. II. Evidence for overlapping sources and involvement of auditory cortex.

作者信息

Wood C C, Wolpaw J R

出版信息

Electroencephalogr Clin Neurophysiol. 1982 Jul;54(1):25-38. doi: 10.1016/0013-4694(82)90228-0.

DOI:10.1016/0013-4694(82)90228-0
PMID:6177515
Abstract

The scalp distributions of human auditory evoked potentials (AEPs) between 20 and 250 msec were investigated using non-cephalic reference recordings. AEPs to binaural click stimuli were recorded simultaneously from 20 scalp locations over the right hemisphere in 11 subjects. Computer-generated isovoltage topographic maps at high temporal resolution were used to assess the stability of AEP scalp distributions over time and relate them to major peaks in the AEP wave forms. For potentials between 20 and 60 msec, the results demonstrate a stable scalp distribution of dipolar form that is consistent with sources in primary auditory cortex on the superior temporal plant near the temporoparietal junction. For potentials between 60 and 250 msec, the results demonstrate changes in AEP morphology across electrode locations and changes in scalp distribution over time that lead to two major conclusions. First, AEPs in this latency period are generated by multiple sources which partially overlap in time. Second, one or more regions of auditory cortex contribute significantly to AEPs in this period. Additional data are needed to determine the relative contribution of auditory cortex sources on the superior temporal plane and the lateral temporal surface and to identify AEP sources outside the temporal lobe.

摘要

使用非头部参考记录研究了20至250毫秒之间人类听觉诱发电位(AEP)的头皮分布。在11名受试者的右半球20个头皮位置同时记录了对双耳点击刺激的AEP。使用高时间分辨率的计算机生成等电压地形图来评估AEP头皮分布随时间的稳定性,并将其与AEP波形中的主要峰值相关联。对于20至60毫秒之间的电位,结果表明偶极形式的头皮分布稳定,这与颞顶叶交界处附近颞上平面初级听觉皮层中的源一致。对于60至250毫秒之间的电位,结果表明跨电极位置的AEP形态变化以及随时间的头皮分布变化,得出两个主要结论。首先,此潜伏期的AEP由多个在时间上部分重叠的源产生。其次,在此期间,一个或多个听觉皮层区域对AEP有显著贡献。需要更多数据来确定颞上平面和颞外侧表面的听觉皮层源的相对贡献,并识别颞叶以外的AEP源。

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