Krug H
Gegenbaurs Morphol Jahrb. 1981;127(5):593-6.
The discrimination between normal aging and disease is very difficult, especially in the vascular system. The main factors, gene expression, physical forces, and environmental conditions are effective in normal and pathological circumstances. The changes in extracellular and cellular level are described. During aging, a fibrosis and a reduction of the cellular functions in the vascular wall are found. This deteriorates the blood streaming and favours pathological processes, e.g. atherosclerosis.
区分正常衰老和疾病非常困难，尤其是在血管系统中。主要因素，即基因表达、物理力和环境条件，在正常和病理情况下都起作用。文中描述了细胞外和细胞水平的变化。在衰老过程中，发现血管壁出现纤维化且细胞功能减退。这会使血流恶化并助长病理过程，如动脉粥样硬化。
