通过口服活细胞对小鼠进行耶尔森氏小肠结肠炎杆菌和假结核耶尔森氏菌粪便排泄的交叉保护。
Cross-protection against fecal excretion of Yersinia enterocolitica and Yersinia pseudotuberculosis in mice by oral vaccination of viable cells.
作者信息
Uchida I, Kaneko K, Hashimoto N
出版信息
Infect Immun. 1982 May;36(2):837-40. doi: 10.1128/iai.36.2.837-840.1982.
Abstract
Mice given orally either the O3, O9, or O5B serovar of Yersinia enterocolitica showed protection upon subsequent oral challenge with another of these strains. Excretion of serovar O3 in the feces was inhibited in mice surviving oral challenge with Yersinia pseudotuberculosis IVA. Cross-reaction of O antigen among these four strains was 32 or more times lower than the homologous titers.
摘要
口服小肠结肠炎耶尔森菌O3、O9或O5B血清型的小鼠，在随后用这些菌株中的另一种进行口服攻击时表现出保护作用。在用假结核耶尔森菌IVA进行口服攻击存活的小鼠中，粪便中O3血清型的排泄受到抑制。这四种菌株之间O抗原的交叉反应比同源滴度低32倍或更多。
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