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新型分析试剂在香豆素修饰血浆中的应用效果

Usefulness of new analytical reagents demonstrated with coumadin-modified plasma.

作者信息

Seegers W H, Elkstrom M E, Harper C A, Hassouna H I

出版信息

Bibl Haematol. 1977;44:61-7. doi: 10.1159/000402151.

DOI:10.1159/000402151
PMID:617784
Abstract

Prothrombin, factor X or factor IX were removed specifically from bovine plasma by immunological techniques. Each depleted plasma is responsive to the respective purified component, and was used to follow the blood changes produced in a steer's blood by Coumadin administration. A factor IX-VII reagent was also used to follow changes in factor IX and factor VII activity. It is suggested that the new reagents may have practical value for qualitative and quantitative work in blood coagulation studies.

摘要

通过免疫技术从牛血浆中特异性去除凝血酶原、因子X或因子IX。每种贫化血浆对各自的纯化成分有反应,并用于追踪在一头公牛血液中通过给予香豆素所产生的血液变化。还使用了一种因子IX - VII试剂来追踪因子IX和因子VII活性的变化。有人认为,这些新试剂可能在凝血研究的定性和定量工作中具有实用价值。

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