The absence of substance P from guinea pig auditory structures.

The following auditory structures were examined for Substance-P-Containing cells and fibres using a monoclonal antibody: organ of Corti, spiral ganglion, auditory nerve, cochlear nucleus. No substance P was detected in any of these structures. Giving due consideration to the sensitivity and specificity of this method of detection, it was concluded that Substance P has no function in the lower auditory system of the guinea pig.