Neidhardt B, Schricker K T
Fortschr Med. 1982 May 13;100(18):836-40.
Hemostatic changes in liver cirrhosis regularly have complex causes. In addition to a quantitative deficiency of hemostatic factors, also qualitative changes in coagulation factors, disturbances in coagulation factor metabolism and possible iatrogenic disturbances in plasmatic and thrombocytic hemostatic mechanism are to be considered. To diagnose a deficit of hemostatic factors is no problem, but to answer the question which of the numerous pathogenetic factors dominates in an individual case at this moment is very difficult and often impossible.
肝硬化中的止血变化通常有复杂的病因。除了止血因子的数量不足外，还应考虑凝血因子的质量变化、凝血因子代谢紊乱以及血浆和血小板止血机制中可能的医源性紊乱。诊断止血因子缺乏并不困难，但要回答在个别病例中众多致病因素中目前哪一个占主导地位这个问题非常困难，而且往往是不可能的。
