Droy M T, Michel P F
Nouv Presse Med. 1982 Apr 8;11(16):1201-5.
The authors make an attempt of dating up our knowledge of the functions which interfere with the peripheral nerves regeneration after an injury by a traumatism or an another pathological cause. The lesion of a nerve fiber causes changes on the cellular body, on the distal segment and on the glial environment. The regeneration which is a physiological phenomenon, is conditioned by the importance of the injury and the location of the injury. The regeneration require an important increase of the protein synthesis, specially the cytoskeleton proteins. This cytoskeleton is essential for the maintenance of axonal transports which control the arrival of materials requested for the fiber growth and for its functional recovery.
作者试图更新我们对于因创伤或其他病理原因导致损伤后干扰周围神经再生功能的认识。神经纤维损伤会导致细胞体、远端节段以及神经胶质环境发生变化。再生作为一种生理现象,取决于损伤的严重程度和损伤部位。再生需要蛋白质合成显著增加,尤其是细胞骨架蛋白。这种细胞骨架对于维持轴突运输至关重要,轴突运输控制着纤维生长及其功能恢复所需物质的到达。