Meurala H, Hekali P, Valle M, Frick M H, Harjola P T
Thorac Cardiovasc Surg. 1982 Apr;30(2):99-102. doi: 10.1055/s-2007-1022222.
To study the effectiveness of sequential vein grafts in coronary bypass surgery, left ventricular (LV) function was serially estimated in 28 patients with sequential grafts and compared with that in 24 patients with multiple single vein grafts. Early patency of sequential grafts was 98% vs. 94% for single veins. Late patency (mean 28 months after operation) of sequential veins was 97% vs. 85% for single vein grafts (mean 32 months after operation). Various parameters of resting LV function (pressure, volumes, ejection fraction, regional contraction score, mean velocity of fiber shortening) showed only slight and non-significant changes during the angiographic follow-up in the sequential vein graft group, with the exception of LVEDP, which was significantly lower at the late follow-up (p less than 0.05). There was an apparently spurious highly significant decline in fiber shortening velocity in the sequential graft group (p less than 0.001). Division of the series into subgroups of complete or incomplete revascularization did not improve the predictive power of resting LV function. The data reveal that sequential vein grafts are comparable to multiple single vein grafts as far as the influence on LV function at rest is concerned.
为研究序贯静脉移植物在冠状动脉搭桥手术中的有效性,对28例接受序贯移植物的患者的左心室(LV)功能进行了连续评估,并与24例接受多根单静脉移植物的患者进行了比较。序贯移植物的早期通畅率为98%,单根静脉为94%。序贯静脉的晚期通畅率(术后平均28个月)为97%,单静脉移植物为85%(术后平均32个月)。静息LV功能的各项参数(压力、容积、射血分数、局部收缩评分、纤维缩短平均速度)在序贯静脉移植物组的血管造影随访期间仅显示轻微且无显著变化,但LVEDP除外,其在晚期随访时显著降低(p<0.05)。序贯移植物组的纤维缩短速度明显出现了高度显著的假性下降(p<0.001)。将该系列分为完全或不完全血运重建亚组并未提高静息LV功能的预测能力。数据显示,就对静息LV功能的影响而言,序贯静脉移植物与多根单静脉移植物相当。