Meurala H
Ann Clin Res. 1983 Apr;15(2):55-61.
The effect of aortocoronary bypass surgery on exercise tolerance in 34 patients undergoing sequential saphenous vein bypass grafts (seq. SVBG) was compared with that in 38 patients who had undergone single SVBGs. Postoperative exercise testing was carried out on average 23 months after surgery in the seq. SVBG group and 27 months after surgery in the single SVBG group (range 10-62 months in both groups). At the time of follow-up complete revascularization was demonstrated in 59% of the patients in the seq. SVBG group and in 50% of the patients in the single SVBG group. The improvement in the maximal load (MaxL) at the follow-up was 90.0% (p less than 0.001) in the seq. SVBG and 41.3% (p less than 0.001) in the single SVBG group. The corresponding increase in maximal heart rate (MaxHR) was 12.5% (p less than 0.001) and 10.1% (p less than 0.001) and the maximal ST depression (MaxSTd) diminished by 70.4% (p less than 0.001) and 54.2% (p less than 0.001). There were no statistically significant differences between the groups with respect to changes in MaxL, MaxHR and MaxSTd postoperatively. The changes in MaxL, MaxHR and MaxSTd in the completely and incompletely revascularized subgroups did not differ statistically. The exercise tolerance in this study was at least as good in the seq. SVBG group as in the single SVBG group and fully justifies continuing bypass surgery with sequential vein grafts.
将34例行序贯大隐静脉搭桥术（seq. SVBG）患者的主动脉冠状动脉搭桥手术对运动耐量的影响，与38例行单支大隐静脉搭桥术患者的情况进行了比较。序贯大隐静脉搭桥术组术后平均23个月进行运动测试，单支大隐静脉搭桥术组术后平均27个月进行运动测试（两组范围均为10 - 62个月）。随访时，序贯大隐静脉搭桥术组59%的患者实现了完全血运重建，单支大隐静脉搭桥术组为50%。随访时，序贯大隐静脉搭桥术组最大负荷（MaxL）的改善为90.0%（p < 0.001），单支大隐静脉搭桥术组为41.3%（p < 0.001）。相应地，最大心率（MaxHR）的增加分别为12.5%（p < 0.001）和10.1%（p < 0.001），最大ST段压低（MaxSTd）分别减少了70.4%（p < 0.001）和54.2%（p < 0.001）。两组术后MaxL、MaxHR和MaxSTd的变化在统计学上无显著差异。完全血运重建和不完全血运重建亚组中MaxL、MaxHR和MaxSTd的变化在统计学上无差异。本研究中序贯大隐静脉搭桥术组的运动耐量至少与单支大隐静脉搭桥术组一样好，完全证明继续采用序贯静脉搭桥进行搭桥手术是合理的。
