Kradin R L, Young R H, Dickersin G R, Kirkham S E, Mark E J
Am J Surg Pathol. 1982 Mar;6(2):165-72. doi: 10.1097/00000478-198203000-00009.
A tumor of the lung in a 35-year-old woman contained numerous complex, branching tubules resembling the developing fetal lung in its canalicular state. Some of the epithelial cells within the tubules were argyrophilic, and electron microscopy demonstrated the dense-core neurosecretory-type cytoplasmic granules. These characteristics support an endodermal origin for this neoplasm. Morphologically the tubules are similar to the epithelial component seen in pulmonary blastoma, but the tumor lacks the sarcomatous areas integral to the concept of blastoma. The designation pulmonary endodermal tumor resembling fetal lung may better describe this unusual neoplasm.
一名35岁女性的肺部肿瘤包含许多复杂的分支小管，类似于处于小管期的发育中的胎儿肺。小管内的一些上皮细胞呈嗜银性，电子显微镜显示有致密核心的神经分泌型细胞质颗粒。这些特征支持该肿瘤起源于内胚层。形态学上，这些小管类似于肺母细胞瘤中所见的上皮成分，但该肿瘤缺乏肺母细胞瘤概念中不可或缺的肉瘤区域。“类似胎儿肺的肺内胚层肿瘤”这一命名可能更能描述这种不寻常的肿瘤。
