Sherman H, Sandberg S, Fineberg H V
J Chronic Dis. 1982;35(9):743-50. doi: 10.1016/0021-9681(82)90098-4.
Analyzing nine available studies of cardiac dysrhythmia among males shows an exponential increase of the prevalence of dysrhythmia with increased age (16-74 yr). This pattern appears in unselected populations and in populations selected for prior history of myocardial infarction. In 6 of 9 population groups the exponent for the rate of increased prevalence of any ventricular premature contractions (VPCs) with age was statistically indistinguishable from study to study despite variations in length of monitoring, of local interpretations of ECG, or of differences in the composition of these groups. Within each population group the prevalence of "frequent" VPCs or of "complex" VPCs also increased exponentially with age. The precise mathematical expression for the increase suggests an etiologic explanation for cardiac dysrhythmia common to coronary artery disease and myocardial infarctions which exhibit similar behavior.
对九项关于男性心律失常的现有研究进行分析后发现，心律失常的患病率随着年龄增长（16 - 74岁）呈指数级上升。这种模式在未经过筛选的人群以及有心肌梗死病史的选定人群中均有出现。在9个人群组中的6个群组里，尽管监测时长、心电图的本地解读方式或这些群组的构成存在差异，但任何室性早搏（VPC）患病率随年龄增长的速率指数在各研究之间在统计学上并无显著差异。在每个群组中，“频发”VPC或“复杂”VPC的患病率也随年龄呈指数级上升。这种增长的确切数学表达式为冠状动脉疾病和心肌梗死共有的心律失常病因提供了一种解释，而这两种疾病表现出相似的行为。
