Schramm H J, Schramm W
Hoppe Seylers Z Physiol Chem. 1982 Aug;363(8):803-12. doi: 10.1515/bchm2.1982.363.2.803.
From electron micrographs single molecules of alpha 2-macroglobulin in the "closed" form, the "open" form and as the trypsin complex have been computer averaged. The molecular images are discussed. Molecules of the electrophoretically fast migrating "F-form" have the "closed" form. In the case of the alpha 2-macroglobulin/trypsin complex the two attached trypsin molecules are located very near to each other and in the central part of the alpha 2-macroglobulin molecule.
通过电子显微镜，已对处于“封闭”形式、“开放”形式以及作为胰蛋白酶复合物的α2-巨球蛋白单分子进行了计算机平均处理。对分子图像进行了讨论。电泳快速迁移的“F型”分子呈“封闭”形式。在α2-巨球蛋白/胰蛋白酶复合物的情况下，两个附着的胰蛋白酶分子彼此非常靠近，且位于α2-巨球蛋白分子的中央部分。
