Hanson F W
J Reprod Med. 1982 Jul;27(7):423-7.
Seventy-one patients participated, during three dysmenorrheic episodes, in a study that combined a double-blind parallel comparison of naproxen sodium and ibuprofen to each other with a single-blind comparison of naproxen sodium and ibuprofen to a placebo. The comparative measures of efficacy included hourly and overall ratings of pain by patients, limitation of daily activity due to pain and the need for additional pain medication. Although none of these measures showed a statistically significant difference, an analysis of the differences that did emerge showed a trend slightly favoring naproxen sodium. Both drugs were highly effective and significantly superior to the placebo.
71名患者在三个痛经发作期参与了一项研究，该研究将萘普生钠和布洛芬相互进行双盲平行比较，并将萘普生钠和布洛芬与安慰剂进行单盲比较。疗效的比较指标包括患者每小时和总体的疼痛评分、因疼痛导致的日常活动受限以及对额外止痛药物的需求。尽管这些指标均未显示出统计学上的显著差异，但对出现的差异进行分析后发现，有略微倾向于萘普生钠的趋势。两种药物都非常有效，且显著优于安慰剂。
