细胞色素P450 IID的分子遗传学。药物代谢异常。 - Suppr

Suppr

超能文献

Molecular genetics of cytochrome P450 IID. Anomalies of drug metabolism.

作者信息

Jacqz-Aigrain E, Panserat S, Sica L, Krishnamoorthy R

机构信息

INSERM Unité 120, Robert Debré Hospital, Paris, France.

出版信息

Clin Rev Allergy Immunol. 1995 Fall;13(3):211-21. doi: 10.1007/BF02771762.

DOI:10.1007/BF02771762

PMID:8535928

Abstract

摘要

相似文献

Molecular genetics of cytochrome P450 IID. Anomalies of drug metabolism.细胞色素P450 IID的分子遗传学。药物代谢异常。

Clin Rev Allergy Immunol. 1995 Fall;13(3):211-21. doi: 10.1007/BF02771762.

Interactions of serotonin reuptake inhibitors with tricyclic antidepressants.

Arch Gen Psychiatry. 1995 Sep;52(9):783-5. doi: 10.1001/archpsyc.1995.03950210077014.

A polymorphic CfoI site in exon 6 of the human cytochrome P450 CYP2D6 gene detected by the polymerase chain reaction.

Hum Genet. 1993 Jul;91(6):616-7. doi: 10.1007/BF00205091.

Predicting the cytochrome P450 mediated metabolism of xenobiotics.预测细胞色素P450介导的外源化合物代谢。

Pharmacogenetics. 1993 Feb;3(1):1-18. doi: 10.1097/00008571-199302000-00001.

A BamHI polymorphism in the human cytochrome P450 gene, CYP2D6.人类细胞色素P450基因CYP2D6中的BamHI多态性。

Clin Genet. 1995 Feb;47(2):103-4. doi: 10.1111/j.1399-0004.1995.tb03934.x.

Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: the effect of the expression of cytochrome b(5) with recombinant P450 enzymes.在药物发现早期阶段预测细胞色素P450酶对药物代谢贡献的方法：细胞色素b(5)与重组P450酶共表达的影响

Xenobiotica. 2007 Sep;37(9):986-99. doi: 10.1080/00498250701620692.

Pharmacogenetics of cytochromes P450.细胞色素P450的药物遗传学

Mol Aspects Med. 1999 Feb-Apr;20(1-2):12-24, 25-137. doi: 10.1016/s0098-2997(99)00005-9.

Recombinant human cytochrome P450 monooxygenases for drug metabolite synthesis.用于药物代谢物合成的重组人细胞色素 P450 单加氧酶。

Biotechnol Bioeng. 2010 Aug 1;106(5):699-706. doi: 10.1002/bit.22775.

[Genetic polymorphism of drug metabolizing enzymes].[药物代谢酶的基因多态性]

Seikagaku. 1997 Oct;69(10):1196-9.

Homology modelling of human cytochromes P450 involved in xenobiotic metabolism and rationalization of substrate selectivity.参与外源性物质代谢的人类细胞色素P450的同源性建模及底物选择性的合理化分析

Exp Toxicol Pathol. 1999 Jul;51(4-5):369-74. doi: 10.1016/S0940-2993(99)80024-4.

本文引用的文献

Molecular heterogeneity of the XbaI defined 44kb allele of the CYP2D locus within the Caucasian population.白种人群体中CYP2D基因座XbaI定义的44kb等位基因的分子异质性。

Br J Clin Pharmacol. 1993 Feb;35(2):161-5. doi: 10.1111/j.1365-2125.1993.tb05681.x.

Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype.

Hum Mol Genet. 1994 Jun;3(6):923-6. doi: 10.1093/hmg/3.6.923.

A missense mutation in exon 6 of the CYP2D6 gene leading to a histidine 324 to proline exchange is associated with the poor metabolizer phenotype of sparteine.

Naunyn Schmiedebergs Arch Pharmacol. 1994 Oct;350(4):434-9. doi: 10.1007/BF00178963.

The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature.细胞色素P450超家族：新序列、基因图谱、登录号、酶的早期俗名及命名法的更新

DNA Cell Biol. 1993 Jan-Feb;12(1):1-51. doi: 10.1089/dna.1993.12.1.

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.对英国白人人群中异喹胍氧化遗传多态性的家系及群体研究。

J Med Genet. 1980 Apr;17(2):102-5. doi: 10.1136/jmg.17.2.102.

High-performance liquid chromatography technique for resolving multiple forms of hepatic membrane-bound cytochrome P-450.用于分离多种形式肝膜结合细胞色素P-450的高效液相色谱技术

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6473-5. doi: 10.1073/pnas.77.11.6473.

Human pharmacogenetics: Introduction.人类药物遗传学：引言

Fed Proc. 1984 May 15;43(8):2295-7.

Metabolic oxidation phenotypes as markers for susceptibility to lung cancer.代谢氧化表型作为肺癌易感性的标志物。

Nature. 1984;312(5990):169-70. doi: 10.1038/312169a0.

Assessment of methods to identify sources of interindividual pharmacokinetic variations.个体间药代动力学差异来源识别方法的评估

Clin Pharmacokinet. 1983 Sep-Oct;8(5):378-409. doi: 10.2165/00003088-198308050-00002.

Multiple forms of cytochrome P-450 and the importance of molecular biology and evolution.细胞色素P-450的多种形式以及分子生物学和进化的重要性。

Biochem Pharmacol. 1982 Jul 15;31(14):2311-7. doi: 10.1016/0006-2952(82)90523-8.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验