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[利用35S-硫酸钠测量细胞外液的临床应用(作者译)]

[Clinical application of extracellular fluid measurement using 35S-sodium sulfate (author's transl)].

作者信息

Shionoiri H, Kondo K, Uneda S, Goto E, Ono Y, Ujiie M, Nozawa T

出版信息

Radioisotopes. 1977 Sep;26(9):606-12. doi: 10.3769/radioisotopes.26.9_606.

DOI:10.3769/radioisotopes.26.9_606
PMID:618188
Abstract

ECF (extracellular fluid volume) was measured by 35S-sodium sulfate and the same time value of PV (plasma volume) was determined by 131I-RISA in each subject. In normal ECF was an average of 181 ml/kg, 6.21 l/m2 and PV was 49.1 ml/kg, 1.69 l/m2. Both values of ECF and PV in essential hypertension were almost the same as those in normal. In congestive heart failure ECF was 232 ml/kg, 7.51 l/m2 and PV was 55.8 ml/kg, 1.80 l/m2. In the patients with ascites or edema, ECF was 256 ml/kg, 8.69 l/m2 and PV was 53.0 ml/kg, 1.79 l/m2. The results of the measurement by the two compounds also corresponded to the conditions of the patients who showed electrolytes disorders (ACTH deficiency, SIADH) and was improved by treatment.

摘要

通过35S-硫酸钠测量细胞外液量(ECF),并同时通过131I-人血清铁蛋白测定每位受试者的血浆量(PV)。正常情况下,ECF平均为181毫升/千克、6.21升/平方米,PV为49.1毫升/千克、1.69升/平方米。原发性高血压患者的ECF和PV值与正常情况几乎相同。充血性心力衰竭患者的ECF为232毫升/千克、7.51升/平方米,PV为55.8毫升/千克、1.80升/平方米。腹水或水肿患者的ECF为256毫升/千克、8.69升/平方米,PV为53.0毫升/千克、1.79升/平方米。两种化合物的测量结果也与出现电解质紊乱(促肾上腺皮质激素缺乏、抗利尿激素分泌失调综合征)且经治疗后病情改善的患者情况相符。

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