鼻咽淋巴上皮瘤。借助角蛋白免疫组化显示进行组织学诊断。
Nasopharyngeal lymphoepithelioma. Histological diagnosis as aided by immunohistochemical demonstration of keratin.
作者信息
Miettinen M, Lehto V P, Virtanen I
出版信息
Virchows Arch B Cell Pathol Incl Mol Pathol. 1982 Aug;40(2):163-9.
PMID:6182682
Abstract
Eight cases of primary and metastatic nasopharyngeal lymphoepithelioma and four cases of malignant lymphoma of the pharyngeal region were studied for the presence of keratin by indirect immunofluorescence microscopy. The results showed that all the cases of primary and metastatic lymphoepithelioma contained keratin-positive cells, whereas all the lymphomas were negative for keratin. Anti-keratin antibody thus seems to be a valuable aid in the differential diagnosis between lymphoepithelioma and lymphoma.
摘要
对8例原发性和转移性鼻咽淋巴上皮瘤及4例咽区恶性淋巴瘤进行了间接免疫荧光显微镜检查，以检测角蛋白的存在。结果显示，所有原发性和转移性淋巴上皮瘤病例均含有角蛋白阳性细胞，而所有淋巴瘤对角蛋白均呈阴性。因此，抗角蛋白抗体似乎有助于淋巴上皮瘤和淋巴瘤的鉴别诊断。
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