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C243干扰素与L细胞干扰素各组分之间的抗原相关性。

Antigenic correlations between components of C243 and L cell interferons.

作者信息

Kawade Y, Aguet M, Tovey M G

出版信息

Antiviral Res. 1982 Aug;2(3):155-9. doi: 10.1016/0166-3542(82)90017-1.

Abstract

The three components of virus-induced interferon (IFN) from C243 cells, with molecular weights of 19,000, 24,000 and 30,000, were examined for neutralization by antisera against the alpha (24,000) and beta (36,000) types of virus-induced L cell IFN. The results indicated that the C243 19,000 component belongs to the alpha type, and the 24,000 and 30,000 components to the beta type. The 19,000 component was also indistinguishable from L cell IFN-alpha in the reaction with antisera against human IFN-alpha.

摘要

对来自C243细胞的病毒诱导干扰素(IFN)的三种成分(分子量分别为19,000、24,000和30,000),用针对α型(24,000)和β型(36,000)病毒诱导的L细胞IFN的抗血清进行中和试验。结果表明,C243的19,000成分属于α型,24,000和30,000成分属于β型。在与抗人IFN-α的抗血清反应中,19,000成分也与L细胞IFN-α无法区分。

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