Wiltshaw E, Gowing N F, Stuart-Harris R, Raju S, Barker G H
J R Soc Med. 1982 Nov;75(11):888-92. doi: 10.1177/014107688207501113.
Eight patients presenting with endodermal sinus tumour of the ovary have been treated with combination chemotherapy using cisplatin, bleomycin and vinblastine (PVB). Complete remission occurred in 7 out of 8 cases, all of whom are alive and well 3 to 33 months later. These preliminary results are compared with our own past experience and recent reports in the literature. It is concluded that the PVB regimen is probably as effective in female germ cell tumours as it is in testicular teratoma.
8例卵巢内胚窦瘤患者接受了顺铂、博来霉素和长春花碱(PVB)联合化疗。8例中有7例完全缓解,所有缓解患者在3至33个月后均存活且状况良好。这些初步结果与我们过去的经验以及文献中的近期报道进行了比较。结论是PVB方案在女性生殖细胞肿瘤中的疗效可能与在睾丸畸胎瘤中的疗效相同。