Sølling J, From E, Mogensen C E
Acta Derm Venereol. 1982;62(4):325-9.
Circulating immune complexes (CIC) were detected in one of 11 patients with primary syphilis and in 5 of 12 patients with secondary syphilis. The level of CIC was significantly increased in patients with secondary syphilis. Four weeks later a significant decline in CIC was found. No relationship was demonstrated between CIC and affection of the skin, lymph nodes, or kidneys. An increased albumin excretion rate was demonstrated before treatment. No differences were found in the excretion rate of beta-2-microglobulin before or after treatment. Nineteen patients had a Jarisch-Herxheimer reaction during treatment. An increase in CIC was found in 5 patients and a decrease in 7 patients. No correlation could be demonstrated between the level of or changes in CIC and the severity of the Jarisch-Herxheimer reaction.
11例一期梅毒患者中有1例检测到循环免疫复合物（CIC），12例二期梅毒患者中有5例检测到。二期梅毒患者的CIC水平显著升高。四周后发现CIC显著下降。未发现CIC与皮肤、淋巴结或肾脏受累之间存在关联。治疗前白蛋白排泄率升高。治疗前后β2微球蛋白排泄率未发现差异。19例患者在治疗期间出现了吉海反应。5例患者CIC升高，7例患者CIC降低。未发现CIC水平或变化与吉海反应的严重程度之间存在相关性。
