Sølling J, Sølling K, Jakobsen K U, From E
Acta Derm Venereol. 1978;58(3):263-7.
13 patients with syphilis were investigated regarding the presence of circulating immune complexes by the methods of C 1q-binding-activity and anticomplementarity. Elevated C1q-binding-activity was demonstrated in 6 of 7 patients with secondary syphilis, a significantly greater incidence than among patients with primary syphilis and neurosyphilis. Anticomplementarity was demonstrated in five of seven patients with secondary syphilis and in two patients with neurosyphilis. Anticomplementarity was found in only one of four patients with primary syphilis. The presence of immune complexes may be of importance in the aetiology of some of the lesions of secondary and perhaps tertiary syphilis.
采用C1q结合活性和抗补体方法，对13例梅毒患者循环免疫复合物的存在情况进行了调查。7例二期梅毒患者中有6例C1q结合活性升高，其发生率显著高于一期梅毒和神经梅毒患者。7例二期梅毒患者中有5例以及2例神经梅毒患者显示有抗补体现象。一期梅毒患者4例中仅有1例发现抗补体现象。免疫复合物的存在可能在二期梅毒甚至三期梅毒某些损害的病因学中具有重要意义。
