Polano M K, van der Rhee H J, van der Schroeff J G
Acta Derm Venereol. 1982;62(4):361-4.
Etretinate 0.5 mg/kg body weight combined with 0.1% triamcinolone acetonide and 5% salicylic acid in an O/W cream gave more than 70% improvement in 62% of 75 patients. Of this satisfactorily improved group, at least 41% were still in the same condition after 3 years on a maintenance dose of, on average, 0.3 mg/kg body weight etretinate daily and 20 g weekly of a relatively strong corticosteroid cream. The side effects were acceptable and the convenience for the patients is great as compared with other treatment.
依曲替酯，剂量为0.5毫克/千克体重，与0.1%曲安奈德和5%水杨酸混合制成水包油乳膏，75例患者中有62%病情改善超过70%。在这一改善效果良好的组中，平均每日服用0.3毫克/千克体重依曲替酯并每周使用20克相对强效的皮质类固醇乳膏进行维持治疗3年后，至少41%的患者病情仍维持原状。与其他治疗方法相比，该治疗方法副作用可接受，且对患者来说极为便利。
