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一项对口服低剂量依曲替酯和外用皮质类固醇治疗的银屑病患者进行的为期三年的随访研究。

A three-year follow-up study of psoriasis patients treated with low dosages of etretinate orally and corticosteroids topically.

作者信息

Polano M K, van der Rhee H J, van der Schroeff J G

出版信息

Acta Derm Venereol. 1982;62(4):361-4.

PMID:6183880
Abstract

Etretinate 0.5 mg/kg body weight combined with 0.1% triamcinolone acetonide and 5% salicylic acid in an O/W cream gave more than 70% improvement in 62% of 75 patients. Of this satisfactorily improved group, at least 41% were still in the same condition after 3 years on a maintenance dose of, on average, 0.3 mg/kg body weight etretinate daily and 20 g weekly of a relatively strong corticosteroid cream. The side effects were acceptable and the convenience for the patients is great as compared with other treatment.

摘要

依曲替酯,剂量为0.5毫克/千克体重,与0.1%曲安奈德和5%水杨酸混合制成水包油乳膏,75例患者中有62%病情改善超过70%。在这一改善效果良好的组中,平均每日服用0.3毫克/千克体重依曲替酯并每周使用20克相对强效的皮质类固醇乳膏进行维持治疗3年后,至少41%的患者病情仍维持原状。与其他治疗方法相比,该治疗方法副作用可接受,且对患者来说极为便利。

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