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银屑病治疗与日间护理中心:临床情况及成本效益分析尝试

Psoriasis treatment and a day-care centre: clinical aspects and an attempt at a cost-benefit analysis.

作者信息

Larkö O, Swanbeck G

出版信息

Acta Derm Venereol. 1982;62(5):413-8.

PMID:6183891
Abstract

The practical results of day-care centre treatment of psoriasis have been studied. Patients referred to the centre are generally those where the skin disease covers substantial body areas. The main treatment has been UVB. UVB plus dithranol or PUVA has been used on patients who have failed to respond to UVB alone. With UVB therapy alone, 263/328 patients healed with a median to healing time of 8 weeks, and 9 weeks to relapse. 34/60 patients with a previously poor response to UVB healed on UVB plus dithranol. Median time to healing was 8 weeks and time to relapse, 12 weeks, 24 patients were treated with PUVA, as they had had a poor earlier response to UVB. All healed with a median time to healing of 12 weeks and 25 weeks to relapse. 3.3% of the patients fit for work have at some time during the treatment been off work due to their psoriasis. The cost for this type of treatment is about one-fifteenth of the cost of treatment on a hospital ward.

摘要

对日间护理中心治疗银屑病的实际效果进行了研究。被转诊至该中心的患者通常是皮肤病累及身体大面积区域的患者。主要治疗方法是窄谱中波紫外线(UVB)。对于单独使用UVB治疗无效的患者,采用UVB加蒽林或补骨脂素加长波紫外线(PUVA)治疗。仅采用UVB治疗时,328例患者中有263例治愈,愈合中位时间为8周,复发中位时间为9周。60例先前对UVB反应不佳的患者中,34例在接受UVB加蒽林治疗后治愈。愈合中位时间为8周,复发时间为12周。24例患者因先前对UVB反应不佳而接受PUVA治疗。所有患者均治愈,愈合中位时间为12周,复发时间为25周。3.3%适合工作的患者在治疗期间曾因银屑病而请假。这种治疗方式的费用约为医院病房治疗费用的十五分之一。

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