Cowan M E, Ward K, Woodman C B, Skinner G R
Br J Exp Pathol. 1982 Oct;63(5):472-8.
There were quantitative and qualitative differences in the in-vitro synthesis of 3 polypeptides between squamous and columnar epithelial explants of human cervix. One cross-linked keratin-like polypeptide of mol. wt 50,000 was synthesized and phosphorylated by squamous but not by columnar explants; a second cross-linked keratin-like polypeptide of mol. wt 52,000, which was present in larger amounts in squamous than columnar explants, was both glycosylated and phosphorylated during in-vitro explantation of squamous tissue; a third polypeptide of mol. wt 25,200 which was keratin-like but not cross-linked, was synthesized in squamous-tissue explants but in only 4% of columnar-tissue explants.
人宫颈鳞状上皮和柱状上皮外植体在三种多肽的体外合成上存在数量和质量上的差异。一种分子量为50,000的交联角蛋白样多肽由鳞状上皮外植体合成并磷酸化，而柱状上皮外植体则不能；第二种分子量为52,000的交联角蛋白样多肽，在鳞状上皮外植体中的含量比柱状上皮外植体中多，在鳞状组织体外培养过程中既发生糖基化又发生磷酸化；第三种分子量为25,200的多肽，呈角蛋白样但未交联，在鳞状组织外植体中合成，而在仅4%的柱状组织外植体中合成。
