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[过去20年肝脏及肝外胆管恶性肿瘤的诊断、治疗与预后]

[Diagnosis, treatment and prognosis of malignant tumors of the liver and extrahepatic bile ducts in the last 20 years].

作者信息

Grundmann R, Leichenich A

出版信息

Chirurg. 1982 Sep;53(9):563-70.

PMID:6184203
Abstract

188 patients with primary malignant tumors of the liver, gallbladder and extrahepatic bile ducts are reported. Changes in diagnostics, treatment and survival were analyzed in comparing three periods: 1959-1966, 1967-1974, 1975-1980. A significant improvement of the patient's prognosis could be observed, but this was only based on a decrease of hospital mortality. Radical tumor resection offers the only hope for long-term survival in patients with primary liver tumor. In contrast the carcinoma of the extrahepatic bile duct should be rather treated by palliative surgery. In the case of gallbladder carcinoma the prognosis was already hopeless if the tumor was detected macroscopically during surgery.

摘要

报告了188例原发性肝、胆囊和肝外胆管恶性肿瘤患者。通过比较三个时期(1959 - 1966年、1967 - 1974年、1975 - 1980年)分析了诊断、治疗和生存情况的变化。可以观察到患者预后有显著改善,但这仅基于医院死亡率的降低。根治性肿瘤切除术是原发性肝癌患者长期生存的唯一希望。相比之下,肝外胆管癌应采用姑息性手术治疗。对于胆囊癌,如果在手术中肉眼发现肿瘤,其预后已经无望。

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