Májský A
Folia Haematol Int Mag Klin Morphol Blutforsch. 1982;109(4):655-63.
By using of 1:1000 of diluted antiglobulin sera the cytotoxic antiglobulin test also covers HLA antigens in 20% of those cases which cannot be identified by normal microlymphocytotoxic tests. The percentage of not specifically faulty positive results is lower than 5%. The method can be used for typing HLA antigens in all those cases where a decreased expressiveness of HLA antigens can be expected as well as for determining weak HLA cytotoxins. The use of undiluted antiglobulin sera, however, leads to unspecific positive results in 1/4 of the cases. The reasons for this phenomenon are being investigated and discussed.
通过使用1:1000稀释的抗球蛋白血清，细胞毒性抗球蛋白试验还能检测出20%常规微量淋巴细胞毒性试验无法识别的病例中的HLA抗原。非特异性假阳性结果的比例低于5%。该方法可用于预期HLA抗原表达降低的所有病例的HLA抗原分型，以及确定弱HLA细胞毒素。然而，使用未稀释的抗球蛋白血清会导致四分之一的病例出现非特异性阳性结果。目前正在对这一现象的原因进行调查和讨论。
