Gall F P, Altendorf A, Hermanek P, Gentsch H H
Fortschr Med. 1982 Oct 28;100(40):1876-82.
The results of surgical therapy in 1165 patients with gastric cancer who underwent treatment between 1949 and 1964 are compared with those of 1500 patients who were operated on between 1969 and 1981. Special emphasis is placed on curability, operative methods and postoperative mortality. The 5-year survival rates of patients from the time periods 1950-1959 and 1969-1976 are compared. 1. The percentage of curatively treated patients increased significantly from 46,7% (1949-1964) to 57,0% (1969-1981). 2. The postoperative mortality after total gastrectomy was further reduced significantly: it was 25% from 1957-1964, but only 13% from 1976-1981. 3. The 5-year survival rate of all patients with gastric cancer increased significantly from 10% (1950-1959) to 17% (1969-1976). 4. The 5-year survival rate after curative operations increased from 22% to 30%; after curative distal partial gastrectomy from 22% to 42% and after curative total gastrectomy from 6% to 20%. 5. The median survival time after palliative operations without resection of the tumor was 3 months. Since 1977 more than one third of the patients who could not be treated curatively underwent resection of the tumor. The median survival time in this group is 6 months with improved quality of life.
对1949年至1964年间接受治疗的1165例胃癌患者的手术治疗结果与1969年至1981年间接受手术的1500例患者的结果进行了比较。特别强调了治愈率、手术方法和术后死亡率。比较了1950 - 1959年和1969 - 1976年这两个时间段患者的5年生存率。1. 根治性治疗患者的比例从46.7%(1949 - 1964年)显著增加到57.0%(1969 - 1981年)。2. 全胃切除术后的术后死亡率进一步显著降低:1957 - 1964年为25%,但1976 - 1981年仅为13%。3. 所有胃癌患者的5年生存率从10%(1950 - 1959年)显著增加到17%(1969 - 1976年)。4. 根治性手术后的5年生存率从22%提高到30%;根治性远端部分胃切除术后从22%提高到42%,根治性全胃切除术后从6%提高到20%。5. 未切除肿瘤的姑息性手术后的中位生存时间为3个月。自1977年以来,超过三分之一无法进行根治性治疗的患者接受了肿瘤切除术。该组患者的中位生存时间为6个月,生活质量有所改善。