Siegenthaler U, Laine A, Polak L
J Invest Dermatol. 1983 Jan;80(1):44-7. doi: 10.1111/1523-1747.ep12531034.
Guinea pigs sensitized with either the trivalent chromium chloride or the hexavalent potassium dichromate are capable of reacting in vivo and in vitro to challenges with both chromium salts. This double reactivity is retained also after repeated restimulations with only 1 of these chromium compounds. From the failure to select lymphocytes directed specifically against a chromium determinant of a particular valence it is concluded that by sensitization with chromium salts of different valences a common determinant or closely related determinants are formed. It is suggested that this determinant is formed by chromium in the trivalent form.
用三价氯化铬或六价重铬酸钾致敏的豚鼠，在体内和体外对这两种铬盐的刺激都有反应。只用这两种铬化合物中的一种进行反复再刺激后，这种双重反应性依然存在。由于未能筛选出针对特定价态铬决定簇的特异性淋巴细胞，因此得出结论：通过用不同价态的铬盐致敏，会形成一个共同的决定簇或密切相关的决定簇。有人认为这个决定簇是由三价铬形成的。
