Ordyniec J, Woźniak W, Czerwiński W, Mańkowski T
Probl Med Wieku Rozwoj. 1982;11:223-30.
In 56 cases of children with tumours, the level of alpha-fetoprotein (AFP) was established with radio-immunological method. There were 15 children with neuroblastoma, 13 with ovarian tumours, 14 with sacro-coccygeal tumours, 7 with tumours of liver and 7 with tumours of testis. The level of AFP was elevated in all children with hepatoblastoma, carcinoma embryonale, and malignant teratoma. Monitoring was performed in 15 children with tumours mentioned above. Usefulness of evaluation of AFP level in blood serum in these tumours has been confirmed by diagnosis. In effective treatment of these tumours, AFP level has fallen down to normal. Its rising up again prognosed tumour's relapse several months before.
在56例患肿瘤儿童中,采用放射免疫法测定甲胎蛋白(AFP)水平。其中神经母细胞瘤患儿15例,卵巢肿瘤患儿13例,骶尾部肿瘤患儿14例,肝肿瘤患儿7例,睾丸肿瘤患儿7例。所有肝母细胞瘤、胚胎癌和恶性畸胎瘤患儿的AFP水平均升高。对上述15例肿瘤患儿进行了监测。血清AFP水平评估在这些肿瘤诊断中的作用已得到证实。在这些肿瘤的有效治疗中,AFP水平已降至正常。其再次升高预示肿瘤在数月前复发。