Problems of resistant thrombolysis and early recurrent thrombosis in streptokinase therapy.

Problems of resistant thrombolysis and early rethrombosis during and immediately after streptokinase therapy have been studied with sequential phlebography in 39 patients. Early rethrombosis and resistant thrombolysis were found to correlate with the behavior of plasminogen and fibrinogen to streptokinase. Anticoagulants given during streptokinase therapy do not seem to affect these problems in a dramatic way.