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局部应用牛磺酸对皮质诱发电位的影响。

Alterations of the cortical evoked potential by topical application of taurine.

作者信息

Rossi S T, Bernardi N

出版信息

Electroencephalogr Clin Neurophysiol. 1983 Jan;55(1):102-4. doi: 10.1016/0013-4694(83)90152-9.

DOI:10.1016/0013-4694(83)90152-9
PMID:6185293
Abstract

The effects of topical application of taurine and glycine upon cortical evoked potentials induced by tactile stimulation have been studied in urethane-anaesthetized rats. The amplitudes of both the primary positive component (P1) and the following negative wave (N1) of the evoked potential were markedly increased by the application of 25 mM taurine but were not significantly altered by 25 mM glycine. These results indicate a possible depressant action of taurine at superficial cortical layers.

摘要

在氨基甲酸乙酯麻醉的大鼠中,研究了局部应用牛磺酸和甘氨酸对触觉刺激诱发的皮质诱发电位的影响。应用25 mM牛磺酸可使诱发电位的初级正波成分(P1)和随后的负波(N1)的幅度显著增加,但25 mM甘氨酸对其无明显影响。这些结果表明牛磺酸可能对皮质浅层有抑制作用。

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