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局限性前列腺癌患者血清前列腺抗原检测:与临床病程的相关性

Serum prostatic antigen measurement in localized prostatic cancer: correlation with clinical course.

作者信息

Pontes J E, Chu T M, Slack N, Karr J, Murphy G P

出版信息

J Urol. 1982 Dec;128(6):1216-8. doi: 10.1016/s0022-5347(17)53431-x.

DOI:10.1016/s0022-5347(17)53431-x
PMID:6185699
Abstract

Serial serum prostatic antigen measurements were performed on patients treated for localized prostatic carcinoma. There was good correlation of mean serum prostatic antigen levels and the surgical stage of the disease. Among patients treated by radical prostatectomy there was good correlation of an elevated serum prostatic antigen and the development of metastatic disease. It appears that serum prostatic antigen is a good indicator and predictor of the development of distant metastasis in this group of patients.

摘要

对接受局限性前列腺癌治疗的患者进行了系列血清前列腺抗原测量。血清前列腺抗原平均水平与疾病的手术分期之间存在良好的相关性。在接受根治性前列腺切除术治疗的患者中,血清前列腺抗原升高与转移性疾病的发生之间存在良好的相关性。看来血清前列腺抗原是这组患者远处转移发生的良好指标和预测因子。

相似文献

1
Serum prostatic antigen measurement in localized prostatic cancer: correlation with clinical course.局限性前列腺癌患者血清前列腺抗原检测:与临床病程的相关性
J Urol. 1982 Dec;128(6):1216-8. doi: 10.1016/s0022-5347(17)53431-x.
2
The relationship of prostate specific antigen levels and residual tumor volume in stage A prostate cancer.A期前列腺癌中前列腺特异性抗原水平与残余肿瘤体积的关系。
J Urol. 1990 Nov;144(5):1167-70; discussion 1170-1. doi: 10.1016/s0022-5347(17)39683-0.
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Prostatic specific antigen and prostatic acid phosphatase in the monitoring and staging of patients with prostatic cancer.前列腺特异性抗原和前列腺酸性磷酸酶在前列腺癌患者监测及分期中的应用
J Urol. 1987 Nov;138(5):1181-4. doi: 10.1016/s0022-5347(17)43543-9.
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Comparison of serum prostate specific membrane antigen, prostate specific antigen, and free prostate specific antigen levels in radical prostatectomy patients.前列腺癌根治术患者血清前列腺特异性膜抗原、前列腺特异性抗原及游离前列腺特异性抗原水平的比较
Cancer. 1997 Jul 1;80(1):107-14. doi: 10.1002/(sici)1097-0142(19970701)80:1<107::aid-cncr14>3.0.co;2-1.
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[Clinico-pathologic correlation in patients undergoing surgical staging and radical prostatectomy for prostatic cancer].[前列腺癌患者手术分期及根治性前列腺切除术的临床病理相关性]
Actas Urol Esp. 1993 Feb;17(2):122-5.
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Natural history of disease progression in patients who fail to achieve an undetectable prostate-specific antigen level after undergoing radical prostatectomy.接受根治性前列腺切除术后未能达到前列腺特异性抗原水平不可检测的患者疾病进展的自然史。
Cancer. 2004 Dec 1;101(11):2549-56. doi: 10.1002/cncr.20637.
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Preoperative plasma levels of transforming growth factor beta(1) (TGF-beta(1)) strongly predict progression in patients undergoing radical prostatectomy.术前转化生长因子β1(TGF-β1)的血浆水平可强烈预测接受根治性前列腺切除术患者的病情进展。
J Clin Oncol. 2001 Jun 1;19(11):2856-64. doi: 10.1200/JCO.2001.19.11.2856.
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[Prostate-specific antigen. A new biological serum marker for prostatic adenocarcinoma].[前列腺特异性抗原。前列腺腺癌的一种新的生物血清标志物]
Tidsskr Nor Laegeforen. 1990 Sep 30;110(23):2990-3.
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Radical prostatectomy for stage B2 prostatic cancer.B2期前列腺癌根治性前列腺切除术
J Urol. 1982 Apr;127(4):702-3. doi: 10.1016/s0022-5347(17)54003-3.
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Preoperative serum levels of early prostate cancer antigen (EPCA) predict prostate cancer progression in patients undergoing radical prostatectomy.术前早期前列腺癌抗原(EPCA)水平可预测接受根治性前列腺切除术患者的前列腺癌进展。
Prostate. 2012 Feb;72(3):270-9. doi: 10.1002/pros.21428. Epub 2011 May 31.

引用本文的文献

1
Temporal changes in the clinical approach to diagnosing prostate cancer.前列腺癌诊断临床方法的时间变化。
J Natl Cancer Inst Monogr. 2012 Dec;2012(45):162-8. doi: 10.1093/jncimonographs/lgs038.
2
Epidermal growth factor receptors in human prostate cancer: correlation with histological differentiation of the tumour.人前列腺癌中的表皮生长因子受体:与肿瘤组织学分化的相关性
Br J Cancer. 1989 Jul;60(1):41-4. doi: 10.1038/bjc.1989.216.
3
Prostate-specific antigen. Superior serum marker for prostatic carcinoma.前列腺特异性抗原。前列腺癌的优良血清标志物。
Ir J Med Sci. 1987 May;156(5):138-41. doi: 10.1007/BF02953231.
4
Multiple marker evaluation in prostatic cancer with prostatic acid phosphatase, gamma-seminoprotein and prostate-specific antigen.
Int Urol Nephrol. 1991;23(5):455-63. doi: 10.1007/BF02583989.