胎儿血清甲胎蛋白及其与足月时免疫球蛋白和出生体重的关系。

The fetal serum alpha-fetoprotein and its relationship to immunoglobulins and birth weight at term.

作者信息

Cederqvist L L, Spigelman S, Litwin S D

出版信息

Obstet Gynecol. 1983 Feb;61(2):233-7.

Abstract

The distribution of values of alpha-fetoprotein (AFP) was analyzed in the cord blood of 350 newborns divided into groups according to whether their mothers were normal, preeclamptic, or smokers. In addition, fetal birth weight and fetal IgA and IgM at term were correlated with AFP. Cord serum AFP values showed a unimodal bell-shaped distribution in 269 normal newborns with a mean of 22.7 +/- 11.3 (SD) micrograms/ml. The cord sera of infants of preeclamptic mothers and of smoking mothers showed a similar mean and distribution. As previously observed, AFP was correlated inversely with birth weight. No correlation existed between AFP and fetal Ig levels.

摘要

对350名新生儿的脐带血中甲胎蛋白（AFP）值分布进行了分析，这些新生儿根据其母亲是否正常、患有先兆子痫或吸烟被分成不同组。此外，胎儿出生体重以及足月时胎儿的IgA和IgM与AFP相关。269名正常新生儿的脐带血清AFP值呈单峰钟形分布，均值为22.7±11.3（标准差）微克/毫升。先兆子痫母亲和吸烟母亲所生婴儿的脐带血清显示出相似的均值和分布。如先前观察到的，AFP与出生体重呈负相关。AFP与胎儿Ig水平之间不存在相关性。