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Interaction of human beta-endorphin with the terminal SC5b-9 and "preterminal" SC5b-7 and SC5b-8 complexes of human complement.

作者信息

Schweigerer L, Teschemacher H, Bhakdi S

出版信息

Life Sci. 1982;31(20-21):2275-8. doi: 10.1016/0024-3205(82)90136-9.

DOI:10.1016/0024-3205(82)90136-9
PMID:6186881
Abstract

Human beta-endorphin (beta H-EP) is demonstrated to bind to the "preterminal" SC5b-7 and SC5b-8 complexes and to the terminal SC5b-9 complex of human complement. Detailed binding studies revealed saturability, reversibility and structural specificity of the beta H-EP interaction with high or low affinity non-opiate binding sites on SC5b-7 and SC5b-9 complexes. The high affinity binding sites seem to be located predominantly on C5b, C6 or C7 subunits of the complexes.

摘要

相似文献

1
Interaction of human beta-endorphin with the terminal SC5b-9 and "preterminal" SC5b-7 and SC5b-8 complexes of human complement.
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2
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