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Immunohistochemical study of myelin sheaths formed by oligodendrocytes interacting with dissociated dorsal root ganglion neurons in culture.

作者信息

Mithen F A, Wood P M, Agrawal H C, Bunge R P

出版信息

Brain Res. 1983 Feb 28;262(1):63-9. doi: 10.1016/0006-8993(83)90469-9.

DOI:10.1016/0006-8993(83)90469-9
PMID:6187412
Abstract

The addition of central nervous system (CNS) glial cells to dissociated networks of rat dorsal root ganglion neurons in tissue culture provided a useful system for the study of CNS myelin sheath formation. The CNS myelin basic proteins (BP) and proteolipid protein (PLP) were demonstrable in these cultures by immunoperoxidase techniques. Both BP and PLP were detectable in myelinating oligodendrocytes and CNS myelin sheaths. Anti-BP serum and anti-PLP serum were useful immunohistochemical staining reagents for the identification of myelinating oligodendrocytes and CNS myelin sheaths in tissue culture.

摘要

相似文献

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