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Characterization of functional human alpha 2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol.

作者信息

Gonias S L, Pizzo S V

出版信息

Biochemistry. 1983 Feb 1;22(3):536-46. doi: 10.1021/bi00272a003.

DOI:10.1021/bi00272a003
PMID:6188480
Abstract
摘要

相似文献

1
Characterization of functional human alpha 2-macroglobulin half-molecules isolated by limited reduction with dithiothreitol.
Biochemistry. 1983 Feb 1;22(3):536-46. doi: 10.1021/bi00272a003.
2
Methanethiolation of the liberated cysteine residues of human alpha 2-macroglobulin treated with methylamine generates a derivative with similar functional characteristics as native alpha 2-macroglobulin.用甲胺处理人α2-巨球蛋白释放出的半胱氨酸残基进行甲硫基化反应，生成一种具有与天然α2-巨球蛋白相似功能特性的衍生物。
Eur J Biochem. 1995 Feb 1;227(3):612-6. doi: 10.1111/j.1432-1033.1995.tb20180.x.
3
Isolation and characterization of alpha-macroglobulin from guinea pig plasma.从豚鼠血浆中分离和鉴定α-巨球蛋白
J Biochem. 1986 Jun;99(6):1655-65. doi: 10.1093/oxfordjournals.jbchem.a135640.
4
Changes in trypsin-binding properties and conformation of rabbit alpha-2-macroglobulin on reaction with methylamine.兔α-2-巨球蛋白与甲胺反应后胰蛋白酶结合特性及构象的变化
J Biochem. 1989 Jun;105(6):898-904. doi: 10.1093/oxfordjournals.jbchem.a122776.
5
Conformational changes induced in human alpha 2-macroglobulin by protease and nucleophilic modification.蛋白酶和亲核修饰诱导人α2-巨球蛋白的构象变化。
Biochemistry. 1983 Jul 19;22(15):3647-53. doi: 10.1021/bi00284a017.
6
Functional modifications of alpha 2-macroglobulin by primary amines. Kinetics of inactivation of alpha 2-macroglobulin by methylamine, and formation of anomalous complexes with trypsin.α2-巨球蛋白经伯胺的功能修饰。甲胺使α2-巨球蛋白失活的动力学，以及与胰蛋白酶形成异常复合物的过程。
Biochem J. 1982 Jan 1;201(1):119-28. doi: 10.1042/bj2010119.
7
Binding of proteinases to human alpha 2-macroglobulin with its thioester bonds cleaved by methylamine in the presence of a thiol-group-cyanylating reagent.在硫醇基氰化试剂存在的情况下，蛋白酶与硫酯键被甲胺裂解的人α2-巨球蛋白的结合。
Biochem J. 1985 Oct 15;231(2):451-7. doi: 10.1042/bj2310451.
8
Functional modifications of alpha 2-macroglobulin by primary amines. I. Characterization of alpha 2 M after derivatization by methylamine and by factor XIII.α2-巨球蛋白经伯胺的功能修饰。I. 甲胺和因子XIII衍生化后α2M的特性
J Biol Chem. 1981 Sep 10;256(17):9016-22.
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Changes in alpha 2-macroglobulin conformation by reaction with trypsin and methylamine.α2-巨球蛋白与胰蛋白酶和甲胺反应后的构象变化
Ann N Y Acad Sci. 1983;421:158-9. doi: 10.1111/j.1749-6632.1983.tb18105.x.
10
Characterization of human alpha 2-macroglobulin monomers obtained by reduction with dithiothreitol.用二硫苏糖醇还原获得的人α2-巨球蛋白单体的特性分析。
Biochemistry. 1991 Feb 12;30(6):1545-51. doi: 10.1021/bi00220a015.

引用本文的文献

1
Stoichiometry of reactions of alpha 2-macroglobulin with trypsin and chymotrypsin.α2-巨球蛋白与胰蛋白酶和胰凝乳蛋白酶反应的化学计量学
Biochem J. 1984 Jan 1;217(1):303-8. doi: 10.1042/bj2170303.
2
Further characterization of the platinum-reactive component of the alpha 2-macroglobulin-receptor recognition site.α2-巨球蛋白受体识别位点的铂反应性成分的进一步表征。
Biochem J. 1986 Aug 15;238(1):217-25. doi: 10.1042/bj2380217.
3
Kinetics of the reaction of streptokinase-plasmin complex with purified human and mouse alpha 2-macroglobulin. Implications for mechanism.
链激酶-纤溶酶复合物与纯化的人及小鼠α2-巨球蛋白反应的动力学。对作用机制的启示。
Biochem J. 1989 Dec 15;264(3):745-52. doi: 10.1042/bj2640745.
4
Alpha 2-macroglobulin used to isolate intracellular endopeptidases from mammalian cells in culture.α2-巨球蛋白用于从培养的哺乳动物细胞中分离细胞内肽酶。
Biochem J. 1988 Oct 15;255(2):437-43. doi: 10.1042/bj2550437.
5
The conformational changes of alpha 2-macroglobulin induced by methylamine or trypsin. Characterization by extrinsic and intrinsic spectroscopic probes.甲胺或胰蛋白酶诱导的α2-巨球蛋白的构象变化。通过外在和内在光谱探针进行表征。
Biochem J. 1987 Apr 1;243(1):47-54. doi: 10.1042/bj2430047.
6
Purification and characterization of human alpha 2-macroglobulin conformational variants by non-ideal high performance size-exclusion chromatography.通过非理想高效尺寸排阻色谱法对人α2-巨球蛋白构象变体进行纯化与表征
Biochem J. 1986 Apr 15;235(2):559-67. doi: 10.1042/bj2350559.
7
Characterization of a half-molecular fragment obtained by reduction of human alpha 2-macroglobulin with dithiothreitol. A small-angle X-ray and neutron scattering investigation.
Eur Biophys J. 1985;13(1):25-30. doi: 10.1007/BF00266306.
8
Binding of proteinases to human alpha 2-macroglobulin with its thioester bonds cleaved by methylamine in the presence of a thiol-group-cyanylating reagent.在硫醇基氰化试剂存在的情况下，蛋白酶与硫酯键被甲胺裂解的人α2-巨球蛋白的结合。
Biochem J. 1985 Oct 15;231(2):451-7. doi: 10.1042/bj2310451.
9
Kinetics of the reaction of thrombin and alpha 2-macroglobulin.凝血酶与α2-巨球蛋白反应的动力学
Biochem J. 1985 Oct 15;231(2):417-23. doi: 10.1042/bj2310417.
10
Model of alpha 2-macroglobulin structure and function.α2-巨球蛋白的结构与功能模型。
Proc Natl Acad Sci U S A. 1985 Sep;82(17):5700-4. doi: 10.1073/pnas.82.17.5700.