Meisner H, Schöber J G, Struck E, Lipowski B, Mayser P, Sebening F
Thorac Cardiovasc Surg. 1983 Feb;31(1):21-5. doi: 10.1055/s-2007-1020286.
The application of phrenic nerve pacing is an effective method of respiratory support in adults with certain forms of acquired failure of automatic ventilation. The experience with one infant suffering from congenital central hypoventilation (Ondine's syndrome) is summarized in this report. Stimulation electrodes were implanted on the thoracic portion of each phrenic nerve. After a cumbersome period of intensive medical care and conditioning of the phrenic nerve-diaphragm-system, the patient could be weaned off the respirator. Severe upper airway obstruction, however, required tracheostomy. Bilateral simultaneous pacing has been effective now for more than 2 years providing the desired normal ventilation during sleep. The state of the art of phrenic nerve pacing is described.
膈神经起搏的应用是对某些形式的成人获得性自主通气衰竭进行呼吸支持的有效方法。本报告总结了一名患有先天性中枢性低通气（翁丁氏综合征）婴儿的治疗经验。刺激电极被植入每条膈神经的胸部。经过一段繁琐的强化医疗护理和膈神经 - 膈肌系统调节期后，患者得以脱离呼吸机。然而，严重的上呼吸道梗阻需要进行气管切开术。双侧同步起搏现已有效超过2年，可在睡眠期间提供所需的正常通气。本文描述了膈神经起搏的技术现状。
