Alonso Calderón J L, Garrido García H, Pérez Domínguez T, Mazaira J
Cátedra de Cirugía General, Universidad Autónoma de Madrid.
Cir Pediatr. 1994 Jan;7(1):3-7.
The acute effects of external stimulation were well demonstrated by the turn of the century, but the chronic application had to wait until the advent of the modern pacemaker technology. Since 1983 we have implanted bilateral diaphragm pacing in ten infants and adolescents with quadriplegia and central hypoventilation syndrome. The preferred site of implantation was the thoracic phrenic nerve. The electrophysiological status of the phrenic nerve function has before been determined in all patients. We have got bilateral and continuous ventilation, in all patients, but, in quadriplegics is necessary a conditioning period. Long term stimulation of the phrenic nerves to pace the diaphragm is an effective method of ventilatory support in selected cases.
到本世纪初，外部刺激的急性效应已得到充分证明，但慢性应用则要等到现代起搏器技术出现之后。自1983年以来，我们已为10名患有四肢瘫痪和中枢性通气不足综合征的婴儿和青少年植入了双侧膈肌起搏器。植入的首选部位是胸段膈神经。所有患者之前都已确定膈神经功能的电生理状态。我们让所有患者都实现了双侧持续通气，但对于四肢瘫痪患者，需要一个适应期。长期刺激膈神经以驱动膈肌是某些特定病例中有效的通气支持方法。
