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[通过细胞内注射镧离子鉴定大鼠窦房结起搏细胞]

[Identification of rat sinus node pacemaker cells by intracellular injection of lanthanum ions].

作者信息

Sutiagin P V, Pylaev A S

出版信息

Biull Eksp Biol Med. 1983 May;95(5):93-5.

PMID:6189535
Abstract

Action potentials of pacemaker cells were recorded on an isolated preparation of rat right atrium. Lanthanum ions were injected via a recording microelectrode. The sinus node area was treated for electron microscopy. The electron-dense clusters of lanthanum ions were identified in pacemaker cell organelles, such as cytoplasmic and mitochondrial matrix, external membrane of mitochondria, and inner surface of cytolemma. Treatment with La3+ produced no significant alterations in cellular morphology.

摘要

在大鼠右心房的离体标本上记录起搏细胞的动作电位。通过记录微电极注入镧离子。对窦房结区域进行电子显微镜检查。在起搏细胞的细胞器中发现了电子致密的镧离子簇,如细胞质和线粒体基质、线粒体外膜以及细胞膜内表面。用La3+处理未引起细胞形态的显著改变。

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