Osipova S N, Mezhevikin V V, Gitel'zon I I
Biull Eksp Biol Med. 1983 Jul;96(7):99-101.
The relationship between RNA content in erythrocytes and the erythropoiesis rate was studied at varying exposures as a result of which a simple method for erythropoietic activity testing was proposed. It consists in the measurement of ribonucleic acid content in erythrocytes of mice with a decreased erythropoiesis after administration of the test sample. Erythropoietic activity is determined from the magnitude found. The method suggested is marked by simplicity and higher sensitivity and thus may be applied in clinical medicine and research.