Zoller M, Goodman M L, Cummings C W
Laryngoscope. 1978 Jan;88(1 Pt 1):135-40. doi: 10.1002/lary.1978.88.1.135.
Patients with squamous cell carcinoma of the head and neck with cervical node metastasis were studied retrospectively to delineate the prognostic significance of certain clinical and histologic parameters. The patients were divided into radiated and non-radiated groups for analysis purposes. A good prognosis was found in non-radiated patients with an active nodal plasmacytic inflammatory response. No prognostic information was obtainable in observing the inflammatory response of nodes altered by radiation effects. Extranodal spread of the tumor indicated a poor prognosis for radiated and non-radiated patients, being more significant in the non-radiated ones. Patients receiving preoperative radiation must be separated from non-radiated patients in evaluating host response parameters for prognostic purposes.
对有颈部淋巴结转移的头颈部鳞状细胞癌患者进行回顾性研究，以明确某些临床和组织学参数的预后意义。为便于分析，将患者分为放疗组和未放疗组。未放疗且伴有活跃的淋巴结浆细胞炎性反应的患者预后良好。观察受放疗影响而改变的淋巴结的炎性反应无法获得预后信息。肿瘤的结外扩散表明放疗组和未放疗组患者预后均较差，在未放疗患者中更为显著。在评估宿主反应参数以判断预后时，接受术前放疗的患者必须与未放疗患者分开。
