Bartelink H, Breur K, Hart G, Annyas B, van Slooten E, Snow G
Cancer. 1983 Sep 15;52(6):1008-13. doi: 10.1002/1097-0142(19830915)52:6<1008::aid-cncr2820520613>3.0.co;2-b.
In this study the results of combined radiotherapy and surgery are compared with the results of surgery alone in patients with neck node metastases from squamous cell carcinomas of the head and neck region. Postoperative radiotherapy decreases the recurrence rate in the neck, especially in cases with histologically established extranodal spread. Results of preoperative radiotherapy were similar to those of irradiation after surgery. Postoperative radiotherapy is favored, because it allows a selection of patients for extra treatment on the base of prognostic information, provided by the histologic characteristics of the neck dissection specimen.
在本研究中，对头颈部区域鳞状细胞癌颈部淋巴结转移患者，将放疗与手术联合治疗的结果与单纯手术的结果进行了比较。术后放疗可降低颈部复发率，尤其是在组织学证实有结外扩散的病例中。术前放疗的结果与术后放疗相似。术后放疗更受青睐，因为它允许根据颈部清扫标本的组织学特征所提供的预后信息，选择患者进行额外治疗。
