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[1980年和1981年莱比锡地区记录的抗-D致敏反应及其与IgG抗-D(Rh0)免疫预防的关系]

[Anti-D sensitizations in the Leipzig District recorded in 1980 and 1981 and their relation to IgG-anti-D(Rh0) immunoprophylaxis].

作者信息

Berge H

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1983;110(1):133-45.

PMID:6192048
Abstract

In 173 female anti-D-carriers the course of sensibilization found were analysed with respect to Rh-immunoprophylaxis with IgG-anti-D(Rh0). By subdividing into groups before and after introducing Rh-immunoprophylaxis since 1971 the consequences of anti-D-sensibilization are pointed out after Rh-incompatible transfusions, with neglect of treatment and with legally not required treatment in Rh-negative female patients. In addition, failures are analysed. Further problems are presented by the group of prenatal transplacental haemorrhages appearing as late sensibilizations in pregnancy and raising discussions at the time of immunoprophylaxis. Those examples of the course of immunization being particularly evident are represented as descriptors in the form of "sensibilizing chains".

摘要

在173名抗-D携带者中,分析了使用IgG抗-D(Rh0)进行Rh免疫预防时致敏过程。通过将1971年引入Rh免疫预防前后的患者进行分组,指出了Rh血型不相容输血后、未进行治疗以及Rh阴性女性患者未接受法定必要治疗情况下抗-D致敏的后果。此外,还分析了失败情况。产前经胎盘出血组出现了进一步的问题,这些出血在孕期表现为迟发性致敏,并在免疫预防时引发了讨论。免疫过程中特别明显的那些例子以“致敏链”的形式作为描述呈现出来。

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