[Anti-D sensitizations in the Leipzig District recorded in 1980 and 1981 and their relation to IgG-anti-D(Rh0) immunoprophylaxis].

In 173 female anti-D-carriers the course of sensibilization found were analysed with respect to Rh-immunoprophylaxis with IgG-anti-D(Rh0). By subdividing into groups before and after introducing Rh-immunoprophylaxis since 1971 the consequences of anti-D-sensibilization are pointed out after Rh-incompatible transfusions, with neglect of treatment and with legally not required treatment in Rh-negative female patients. In addition, failures are analysed. Further problems are presented by the group of prenatal transplacental haemorrhages appearing as late sensibilizations in pregnancy and raising discussions at the time of immunoprophylaxis. Those examples of the course of immunization being particularly evident are represented as descriptors in the form of "sensibilizing chains".